PB Serum
Powered by recombinant enzyme technology, PB Serum provides a science-led approach to address concerns such as double chin and jowl fat reduction, acne scarring and nodule management. It goes beyond focusing on volume, hydration and surface improvement, it works through targeted enzyme action for deeper targeting.
What is PB Serum and How It Works?
Developed in Spain by Proteos Biotech, PB Serum brings enzyme science into aesthetic medicine. Proteos Biotech specialises in the research, development and production of recombinant enzymes, combining biotechnology expertise with aesthetic medicine applications. The enzyme based formulations help to support tissue remodelling, skin quality, and skin regeneration.
Table of Contents
TogglePB Serum works through recombinant-enzyme technology, harnessing a combination of 3 recombinant enzymes — Lipase, Collagenase and Lyase work together to shrink fat cells without destroying them, repair fibrosis, remodel the extracellular matrix and support your skin’s natural renewal process.

Lipase
Breaks down fat components

Collagenase
Supports remodelling of collagen fibres

Lyase
Enhances tissue permeability
Why Use PB Serum?
PB Serum Recombinant Enzymes are formulated through a unique biotechnological process known as recombinant DNA technology. This process ensures that the enzymes made are bioidentical in structure and sequence to human enzymes. That means the procedure has low immunogenicity and provides a safe, effective treatment experience, maintaining pureness and naturalness.
Bioremodeling Process
The Bioremodeling Process of PB Serum goes beyond the skin surface to restore and revitalize skin from within. Rather than simply treating surface concerns, it reorganize tissues architecture by targeting the biochemical, cellular and structural causes of aging and skin dysfunction. The treatment works gradually across three key levels: The Extracellular Matrix (ECM), The Interstitial Compartment and Skin’s Resident Cells. The result is healthier and resilient skin over time.
Targeted Concerns for PB Serum

Double Chin
Define jawline naturally

Jowl Fat
Break down unwanted jowl fat & slim face

Acne Scars
Support collagen & tissue remodelling

Nodules
Break down hardened collagen fibres that cause nodules

Cellulite/
Stretch Mark
Reduce dimpling of cellulite & enhance skin elasticity
What Are The Benefits of PB Serum in Singapore?
- Reduce Acne Scar
- Shrink Unwanted Fat
- Face Slimming & Tightening
- Soften Unwanted Nodules/Lumps
- Natural-Looking
- Minimal Downtime
- Biocompatible and Safe
Fat-Dissolving VS PB Serum Treatments
Fat Dissolving treatments work by breaking down the membrane of fat cells, causing the cells to be destroyed. The body then gradually clears them.
However, PB Serum works differently. It contains enzymes that are designed to reduce the volume of fat cells by breaking down the fat stored inside them, without destroying it. It also contains enzymes that act on fibrous tissue for skin tightening effect.
What to Expect After PB Serum?
Days 1–7: Mild swelling, redness, tenderness or bruising may occur at the injection site. These usually subside within a few days.
Weeks 2–4: Noticeable facial contouring & fat reduction.
Weeks 4-8: Results peak during this period as collagen restructuring & fat metabolism process has taken place.
- Double Chin & Jowl Reduction
- Defined Facial Contours
- Enhance Skin Texture
- Reduce Acne Scar / Nodules
FAQ for PB Serum Singapore
How many sessions are needed?
Usually 3 sessions are required depending on each individual’s concerns, targeted areas & severity, spaced 2-4 weeks apart.
Is It painful?
Numbing cream will be applied before the treatment to reduce discomfort throughout the treatment.
Are there any side effects & downtime?
Common Side Effects:
Redness and Swelling: After the injection, temporary redness, swelling, or mild bruising may occur around the treated area. These symptoms are typically mild and fade within a few days.
Tenderness or Discomfort: Some individuals experience tenderness in the treated area, especially within the first few days.
Who is suitable for PB Serum Injectable?
PB Serum Injectable is suitable for those who have:
– Stubborn Fat areas like Double Chin, Jowl, Bra Bulge etc
– Acne scars
– Nodules due to collagen stimulator or filler complication
– Cellulite or Stretch Marks
Is the procedure safe?
The enzymes used in the procedure have the same structure and sequence as human enzymes, offering a low level of immunogenicity, making it pure and safe.
Are there any post-treatment care?
– You should avoid saunas, steam room, swimming and direct sun exposure for 14 days
– Apply sunscreen daily to treated areas
– Avoid intense exercise & heavy sweating for 2-3 days