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Rejuran vs Profhilo: All You Need To Know About Skin Booster

Rejuran vs Profhilo All You Need To Know About Skin Booster

Does your skin feel dull? Well, here you have two proven skinboosters to augment the beauty of your skin. Though numerous treatments can offer an extraordinary boost to your skin, the two most popular options that you will come across among aesthetic treatments include Rejuran and Profhilo. But which is the better skinbooster? Before getting into the Rejuran vs Profhilo arguement, let’s understand something about skin boosters.

Skin boosters, also known as injectable moisturizers, are ideal treatment techniques to combat the skin imperfections like fine lines, wrinkles, pores, acne and dry skin. Along with nourishing the skin, they also help prevent the visible signs of ageing and enhance your skin’s natural healing properties. Injectable moisturizers deliver hyaluronic acid directly into the dermis of your skin to produce a more refined and hydrated texture.

Now, Profhilo and Rejuran are examples of injectable moisturizers that brightens, repairs and hydrates your skin from within, without changing the facial features. Both are skin boosters but they are entirely different from each other.

This article will highlight the difference between Rejuran vs Profhilo while helping you understand their difference in terms of properties. You will be able to determine the best treatment for your skin, so let’s begin.


How do these Skin Boosters Work

How do these Skin Boosters Work?

Skin boosters tend to hydrate and reload the moisture back to your skin. The hyaluronic acid and polynucleotides content of these skin boosters foster the healing abilities and biocompatibility. Skin boosters are injected deep into the dermis and hypodermis areas of the face. Through injection, the active ingredient like PN and HA attracts some of the water molecules on the target site, resulting in instant hydration and revitalization.


Main Difference between Rejuran vs Profhilo

Main Difference between Rejuran vs Profhilo

Profhilo is a powerful bio-stimulator and is generally used to create an intense hydrating, anti-ageing and lifting effect. It can provide a radiant glow and visible lifting effect to your skin, because of the higher concentration of high and low molecular weight of hyaluronic acid.

Profhilo penetrated deep into the subcutaneous layer of the skin. It encourages the production of elastin and collagen in the deeper layer of skin to lift the glow. The deeper subcutaneous layer preserves and promotes the viability of fat stem cells, hence enabling Profhilo to produce much more visible results than just improving the superficial fine lines and skin integrity. It also revitalizes the skin by remodelling the damaged tissues at multi layers of the skin.

Rejuran, on the other hand,  contains salmon DNA fragments, polynucleotide and a small percentage of hyaluronic acid. It hydrates the skin and provides radiant glow. It is not penetrated deep into the skin. The polynucleotide content of Rejuran initiates the skin healing and repairing process by stimulating collagen production in the peripheral layer of skin, dermis. Hence it gives a much more natural-looking result and safer treatment technique than other skin boosters.

Rejuran improves the overall texture of the skin by shrinking large pores, diminishing fine lines and wrinkles, tightening sagging skin. It also strengthens the elasticity of your skin and lightens the dark circles, along with improving the depressed acne scars and stretch marks. But the hydration results of Rejuran are not as visible or long-lasting as Profhilo.


Comparison Rejuran vs Profhilo Procedure

Comparison Rejuran vs Profhilo Procedure

Profhilo is one of the least painful skin booster techniques. The pain is minimal because only 5 injection points are involved per side of the face. It is only injected in the five standardized points on each side of the face called Bio-Aesthetic points. This injection technique is also designed to avoid contact with blood vessels and to distribute the product consistently throughout the face. Profhilo is injected once a month for the first 2 months, followed by injecting every 4-6 months for maintenance.

Rejuran involves over 100 micro-injection points to distribute the product evenly throughout the face. The risk of bruising tends to increase after this skin booster technique because of the involvement of many injection points. These injectables are injected once a month for the first three months and then every 3 to 4 months for maintenance. Small bleb are more common with Rejuran as it is injected into the superficial skin layer.


How to decide which skinbooster is better for you

How to decide which skinbooster is better for you?

Selecting the correct type of skin booster is very important to address the skin or facial concerns in a much more efficient, timely and affordable manner. None of the treatment techniques out of the two is better than the other. Both treatments have their advantages and disadvantages. Also, they can produce an effective result when performed correctly. Every individual has a different skin type, so the best treatment technique and the amount of injectable tend to vary from individual to individual. Before opting for any particular treatment, one must determine which treatment will be the best for them depending on their level of dryness, skin texture, acne scars, pore size, skin laxity etc. Your doctor can suggest the best treatment option depending on your skin type and issues.

Lastly, if you are afraid of injections, Profhilo could be a better choice as it includes only ten injection points for the whole face, whereas Rejuran involves around 100 injection points.



When we compare Rejuran vs Profhilo, people with acne scars, open pores, and sensitive skin would be suitable to opt for Rejuran. One of the significant points to keep in mind is Profhilo is not injected in the upper face, it is only injected in the lower and middle face. So individuals who want to undergo the treatment for dry skin and fine wrinkles of the forehead should opt for Rejuran.

Overall, individuals with ageing skin would be suitable for Profhilo, whereas individuals with younger skin may opt for Rejuran.

All in all, both skin boosters tend to produce quite similar effects at the end. But in a more profound sense, one is better for something, and the other is better for something else. No proper comparison can be made to state which one is the better option. The treatment must be selected according to your age, skin type and problem. It is best to speak to our doctor and they will suggest the best treatment option suited for you.