Rejuran, also known as ‘Baby Skin Booster’, is a unique anti-ageing skin rejuvenation treatment to achieve smooth and supple skin. 

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What is Rejuran

The active ingredient used in Rejuran is polynucleotides (PN), which is derived from Salmon fish DNA. These highly purified long chain polynucleotides are extracted and processed under high pressure and temperature. Being remarkably similar to human DNA, Rejuran is safe and bio-compatible with human skin, without causing immune responses or adverse side effects.


PN promotes favorable cell growth environment that repairs damaged skin cells and stimulate natural production of collagen and elastin. This results in reconstruction and improvement of physical appearance of the skin. Rejuran also has high water binding capacity that bind easily to water molecules and hydrates the skin effectively.

Different types of Rejuran & their usage


Rejuran Healer (2ml)

Rejuran Healer showcases the anti-aging power of polynucleotides, the building blocks of DNA.


These polynucleotide chains derive from an unconventional source – salmon. While salmon lends its omega-3 richness to nutritional supplements, its DNA extract brings rejuvenating benefits directly to the skin.


Suitable for face, neck & eye for facial rejuvenation


Rejuran I (1ml)

With a lighter consistency, Rejuran I offers a delicate rejuvenation solution ideal for the sensitive skin surrounding the eyes.


The periorbital area is prone to early signs of aging like crow’s feet, dark circles, and under eye bags. It provides a non-invasive approach to revitalize this fragile area through its innovative polynucleotide formula.


Suitable for thin skin area such as under eye area to reduce dark eye circles


Rejuran S (1ml)

Rejuran S distinguished itself with a thicker viscosity optimized for targeting acne scarring. It goes deeper to repair textural damage from depressed acne scars.


The higher viscosity allows it to remain focused on problem areas that need plumping and smoothing.This collagen buildup fills out and raises depressed scars for improved smoothness.

Suitable for face to reduce acne scars

Rejuran Healer treatment has demonstrated effective results for various skin concerns thanks to its ability to naturally rejuvenate and heal the skin.

What is Rejuran for

Treating dark under eye circles

It can help by stimulating collagen production and increasing blood circulation to brighten and revive the thin, fragile skin around the eyes.


The peptides in Rejuran encourage skin cell turnover to reduce pigmentation and strengthen the delicate eye area. Regular treatments can lead to lighter, less prominent dark circles.

Secret RF for Large Pores treatment

Enlarged pores can also be improved.

 The polynucleotides trigger fibroblasts to boost collagen, plumping and tightening the skin for a smoother surface texture and minimized pore appearance.


It restores the skin barrier function to minimize debris and sebum from clogging pores as well.

Treating Fine Lines and Wrinkles

Smoothing out wrinkles and fine lines

Especially on the face. The increased collagen and elastin synthesis helps fill out wrinkles from within the skin for a more youthful, crease-free complexion.


It also renews the epidermis to reveal fresher, glowier skin that better reflects light to reduce the look of wrinkles.


The skin healing properties also allow Rejuran to repair sun damage that causes premature wrinkling.

Benefits of Rejuran

Here are a myriad of advantages to be gained from this treatment, these includes


How is it administered?

Rejuran Treatment - Topical Anesthesia (30 mins)

1. Topical Anesthesia (30 mins)

Before treatment, a topical numbing cream will be gently applied to the skin area being treated. This anesthetic cream helps minimize discomfort during the procedure.

Rejuran Treatment - Rejuran micro injection

2. Micro-injection (10 mins)

During the treatment, the doctor will administer the injections using ultra-fine needles, either done manually or with an injector device.

3. repair & recovery

Application of Calecim Professional Serum to quickly calm the skin down, reduce redness and accelerate recovery. 


Rejuran - Frequently Asked Questions(FAQ)

Sometimes refer to as Baby Skin Booster, Rejuran Healer, or Miracle Healer Solution, is an innovative anti-aging injectable treatment that aims to revitalize and rejuvenate skin. Unlike other popular injectables like BTX or fillers that address wrinkles and volume loss, it works at a cellular level to stimulate collagen and elastin production and repair damaged skin cells.

It contains a high concentration of polynucleotides, which are chains of nucleic acids that enhance cell renewal and growth. When injected into the skin, these polynucleotides send signals to fibroblast cells to increase collagen and elastin synthesis, as well as encourage tissue regeneration. This results in smoother, firmer, brighter, and more youthful looking skin over time.

Read more about it here
As Rejuran is derived from salmon fish DNA, it’s not for those who are allergic to salmon fish.

Rejuran is not a dermal filler. It is an injectable substance that can stimulate natural production of collagen and elastin. It can also treat skin damage like acne scars, wrinkles and large pores.

The optimal results of a better skin texture and hydration is usually after 1 week as the skin requires time to repair itself from within.

First 3 sessions are best to be done closely on a monthly basis to give an accumulative result. Maintenance treatment of one session every 3 months thereafter is recommended.

With adequate numbing cream and ultra-fine needles, the discomfort is kept to a minimum. Doctor will adjust the injection depth and avoid certain sensitive area to ensure patient’s comfort.

Patient may experience mild redness and swelling which will subside in 1-2 days. Patient can resume the use of make-up and exercise after 2 days, with adequate sunblock.

The treatment has an excellent safety profile with minimal side effects. The main ingredients in it consist of natural polynucleotides that are bio-compatible with human skin cells and tissue.

During the injections, some temporary redness, swelling, or minor bruising may occur at the injection sites, but these are mild inflammatory effects that typically subside within a few hours after the procedure.

The results of the treatment can persist for 6 to 12 months after finishing the necessary sessions. Additional sessions can be done to sustain the effects.

Though Rejuran and BTX are both injectable treatments, their mechanisms differ. Rejuran works by revitalizing the skin through repairing damaged skin cells, making it a popular anti-aging treatment.

Yes it can be combined with other treatments to enhance results for skin rejuvenation, scar treatment, dyspigmentation, BTX, and hydration. Since Rejuran stimulates skin growth and remodeling, using it together with procedures like laser treatments, chemical peels, microneedling, and injectables can optimize and synergize their effects.

Patients should skip makeup and sun exposure for a few days post-treatment. Cosmetics and UV rays can irritate the microinjection sites before they fully heal. This simple precaution allows the polynucleotides to integrate and stimulate renewal undisturbed.